Absolutely! A mentor told me a long time ago that it’s the ear not the gear, so it doesn’t matter.
When I started going freelance, I had an Mbox with stock plug-ins and that’s how I was making money. I was just coming off assisting and I was like “Oh I can do this myself, in my house? Okay.” So I bought the Mbox with the Producer bundle and I had all stock plug-ins. I had the DVerb, the EQ2 (at the time), the stock compressor and the stock deEsser; I just made it work. Obviously now I’ve upgrade quite a bit but I do believe that you can make it work with whatever you have.